
Elizabeth Holmes' lawyer, Amy Saharia, provided several reasons for seeking to overturn Holmes' conviction:

The judges of the 9th US Circuit Court of Appeals had skeptical questions for both sides and did not clearly indicate how they would rule. Circuit Judge Ryan Nelson mentioned that there was "pretty overwhelming evidence" against Holmes, even without the disputed testimony. Circuit Judges Jacqueline Nguyen and Mary Schroeder pointed out that much of Das' testimony concerned his observations at the company, rather than his scientific opinions, as Holmes' lawyer argued. However, Nguyen and Nelson also expressed concerns about the opinions Das was allowed to give during the trial.
Regarding Balwani's case, the judges appeared more skeptical of his lawyer's argument that prosecutors had gone beyond what was in the indictment against him. While the judges did not clearly signal how they would rule, their questioning suggested that they were considering the arguments presented by both sides carefully.

Ramesh "Sunny" Balwani's defense argument regarding the evidence presented against him in the trial was that he acted in good faith and believed in the company's technology1. His defense team sought to shift the blame for any misconduct squarely on Elizabeth Holmes, the CEO of Theranos. They pointed out that Holmes was not only the CEO but also a Silicon Valley star who persuaded investors to pour nearly $1 billion into Theranos. Additionally, Balwani's lawyers emphasized a missing database as a reason for jurors to be skeptical of the prosecution's case. The database contained the company's testing records, but the prosecution was never able to retrieve access before it was destroyed.